Glucocorticoid-dependent regulation of the expression of high-density lipoprotein binding sites in rat hepatocytes |
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| Authors: | A. V. Bocharov Wei Huang E. V. Zaitseva T. G. Vishnyakova E. G. Frolova V. S. Repin J. -L. Nano P. Rompal |
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| Affiliation: | (1) Institute of Experimental Cardiology, Cardiological Research Center, Russian Academy of Medical Sciences, Moscow;(2) Laboratory of Gastroenterology, Nice University, France |
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| Abstract: | It is shown that dexamethasone increases the number of HDL binding sites in cultured hepatocytes bothin vivo andin vitro. The glucocorticoid acts in a dose-dependent and reversible manner within a wide range of concentrations, including physiological and subphysiological doses. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N o 1, pp. 47–50, January, 1994 |
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| Keywords: | high-density lipoproteins hormone regulation glucocorticoids dexamethasone hepatocyte culture adrenalectomized rats |
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