回顾性分析早产儿辅助呼吸相关性肺炎的临床特点及危险因素

目的 探讨早产儿应用呼吸机辅助呼吸后导致呼吸机相关性肺炎（VAP）的临床特点及危险因素.方法 对我院收治的应用呼吸机辅助呼吸后导致VAP的早产儿临床资料进行回顾性分析,对两组机械通气患者发生VAP的危险因素进行比较,对筛选出独立性较好的因素进行多因素逐步Logistic回归分析,总结导致早产儿VAP的临床特点及危险因素.结果 与无VAP患儿比较,VAP患儿胎龄较低、出生体质量较低、机械通气时间较长、留置胃管时间较长、气管插管次数较多,差异均有统计学意义（x2 =6.93,P值均＜0.05）.Logistic回归分析示,出生体质量越重,VAP发生率越低,机械通气时间越长,气管插管次数越多,VAP发生率越高（x2=8.49,P值均＜0.05）.结论 胎龄、出生体质量、机械通气时间、留置胃管时间、气管插管次数是早产儿VAP的危险因素.

Assisted breathing preterm children associated pneumonia clinical features and risk factors

Objective To investigate the application of preterm children after ventilator-assisted breathing cause of ventilator-associated pneumonia （VAP） clinical features and risk factors.Methods Application of our hospital ventilator-assisted breathing lead to premature children after clinical data were retrospectively analyzed VAP,the risk factors in mechanically ventilated patients with VAP groups were compared,for better screening independence multivariate factors Logistic regression analysis,summarized the clinical features lead to preterm children and the risk factors for VAP.Results Compared with patients without VAP,VAP children with lower gestational age,low birth weight,longer duration of mechanical ventilation,longer indwelling stomach tube,endotracheal intubation more frequently,the differences were statistically significant （x2 =6.93,all P 〈0.05）.Logistic regression analysis indicated that the heavier birth weight,the lower the incidence of VAP,duration of mechanical ventilation longer intubation more times higher incidence of VAP group （x2 =8.49,all P 〈0.05）.Conclusions Gestational age,birth weight,duration of mechanical ventilation,indwelling stomach tube time,the number of endotracheal intubation is a risk factor for VAP in premature children.