| 肥胖对气道反应性的影响 |
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| 引用本文： | 彭红,陈平,刘志军.肥胖对气道反应性的影响[J].中国实用内科杂志,2007,27(15):1199-1201. |
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| 作者姓名： | 彭红 陈平 刘志军 |
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| 作者单位： | 中南大学湘雅二医院呼吸内科,湖南,长沙,410011 |
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| 摘 要： | 目的探讨肥胖是否与气道反应性增高有关及是否存在性别差异。方法选择中南大学湘雅二医院肺功能室2003年1月至2006年6月激发试验阳性的气道高反应性患者1180例,分析其体重指数(BMI)与肺功能的相关性;与吸入药物后第一秒用力呼气容积(FEV1)下降百分率达对照值20%时的药物浓度(PC20FEV1)的相关性;并进一步分析男、女患者BMI与PC20FEV1的相关性。结果BMI与用力肺活量(FVC)、FEV1、PC20FEV1均呈负相关(r分别为-0.735,-0.645和-0.044,P均(0.05)。男性患者BMI与PC20FEV1无相关性(P(0.05),女性患者BMI与PC20FEV1呈负相关(r=-0.044,P(0.05)。结论肥胖与肺功能降低及气道反应性增高可能相关,这种影响在女性患者中更明显。成年女性气道反应性较成年男性高。
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| 关 键 词： | 肥胖症 体重指数 气道反应性 |
| 文章编号： | 1005-2194(2007)15-1199-03 |
| 修稿时间： | 2007年2月7日 |
Obesity affects airway reactivity |
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| PENG Hong,CHEN Ping,LIU Zhi-jun.Obesity affects airway reactivity[J].Chinese Journal of Practical Internal Medicine,2007,27(15):1199-1201. |
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| Authors: | PENG Hong CHEN Ping LIU Zhi-jun |
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| Abstract: | Objective To explore if obesity is related to bronchial hyperresponsiveness in different sexuality.Methods A total of 1180 patients with provocation test positive were studied.We analysed the relation of body mass index(BMI)and FVC,FEV1,the relation of BMI and PC_20 FEV1 in all patients and in the men and the women,respectively.Results There was negative correlation between BMI and FVC,FEV_1 of the whole patients.There was also negative correlation between BMI and PC_20FEV_1 of the whole patients and the women but no correlation of the men.PC_20 FEV_1 of men was higher than that of women.Conclusion Obesity is related to the decrease of lung function and the increase of airway responsiveness,this affection is obviously in women.The airway responsiveness of women is higher than that of man. |
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| Keywords: | Obesity Body mass index Airway responsiveness |
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