| 采用风险分类分析局部中晚期鼻咽癌单纯调强放疗疗效 |
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| 引用本文： | 沈关驻,邓小武,吴少雄,肖巍魏,韩非,李安川,赵充.采用风险分类分析局部中晚期鼻咽癌单纯调强放疗疗效[J].中华放射医学与防护杂志,2015,35(7):518-521. |
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| 作者姓名： | 沈关驻 邓小武 吴少雄 肖巍魏 韩非 李安川 赵充 |
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| 作者单位： | 510060 广州, 中山大学肿瘤防治中心放疗科 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心,510060 广州, 中山大学肿瘤防治中心放疗科 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心,510060 广州, 中山大学肿瘤防治中心放疗科 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心,510060 广州, 中山大学肿瘤防治中心放疗科 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心,510060 广州, 中山大学肿瘤防治中心放疗科 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心,510060 广州, 中山大学肿瘤防治中心放疗科 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心,510060 广州, 中山大学肿瘤防治中心放疗科 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心 |
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| 摘 要： | 目的 探讨采用风险分类方法评估局部中晚期鼻咽癌单纯调强放疗疗效的可行性,为前瞻性研究提供依据。 方法 将185例接受单纯调强放疗的局部中晚期鼻咽癌病例,按治疗后死亡风险分为高危组和低危组(无高危因素),高危因素包括下列之一:GTVnx > 30 cm3;T4N2M0期;颈部多个淋巴结转移,其中一个短径 > 4 cm,以及任何T和N3M0期。分析和比较两组病例的临床疗效。 结果 中位随访时间110.9个月(6.7~152.4个月)。高危组和低危组的5年总生存率、局部区域无复发生存率、无远处转移生存率分别为61.0%和90.5%(χ2=30.298,P<0.05)、78.3%和91.5%(χ2=6.352,P<0.05)、71.6% 和92.0%(χ2=16.346,P<0.05)。 结论 该风险分类方法简单易行,可以区分局部中晚期鼻咽癌中的不同失败风险病例,有利于指导临床有针对性开展前瞻性研究。
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| 关 键 词： | 调强放疗 鼻咽癌 风险分类 |
| 收稿时间： | 3/4/2015 12:00:00 AM |
Application of risk category system to evaluate the treatment outcome of locoregionally advanced nasopharyngeal carcinoma treated by intensity-modulated radiation therapy alone |
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| Shen Guanzhu,Deng Xiaowu,Wu Shaoxiong,Xiao Weiwei,Han Fei,Li Anchuan and Zhao Chong.Application of risk category system to evaluate the treatment outcome of locoregionally advanced nasopharyngeal carcinoma treated by intensity-modulated radiation therapy alone[J].Chinese Journal of Radiological Medicine and Protection,2015,35(7):518-521. |
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| Authors: | Shen Guanzhu Deng Xiaowu Wu Shaoxiong Xiao Weiwei Han Fei Li Anchuan and Zhao Chong |
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| Institution: | Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou 510060, China,Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou 510060, China,Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou 510060, China,Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou 510060, China,Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou 510060, China,Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou 510060, China and Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou 510060, China |
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| Abstract: | |
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| Keywords: | Intensity-modulated radiation therapy Nasopharyngeal carcinoma Risk category |
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