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高效液相色谱法测定盐酸曲普立啶纯度与含量的研究
引用本文:李素悦,朱景申. 高效液相色谱法测定盐酸曲普立啶纯度与含量的研究[J]. 华中科技大学学报(医学版), 1999, 0(6)
作者姓名:李素悦  朱景申
作者单位:同济医科大学药学院药物分析教研室!武汉,430030,同济医科大学药学院药物分析教研室!武汉,430030
摘    要:采用高效液相色谱法对盐酸曲普立啶的纯度检验与含量测定方法进行了研究。结果表明,该法在进行盐酸曲普立啶的纯度检验与含量测定时具有良好的精密度与准确性,分离效果与线性关系良好,相关系数为0.9998,最低检出限为40ng,因此可以作为盐酸曲普立啶的纯度检验与含量测定的基本方法。

关 键 词:盐酸曲普立啶  高效液相色谱法  纯度检验  含量测定

Determination of Purity and Content of Triplidine Hydrochloride by HPLC Assay
Li Suyue, Zhu Jingshen. Determination of Purity and Content of Triplidine Hydrochloride by HPLC Assay[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1999, 0(6)
Authors:Li Suyue   Zhu Jingshen
Abstract:HPLC assay was used to determine the purity and content of triprolidine hydrochloride. It was found that the method had high precision and accuracy, fine separation and liner relationship in determining the purity and content of triprolidine hydrochloride, with the coefficients of correlation being 0. 9998. The limit of detection for triprolidine hydrochloride was 4o HPLC assay can be used as a basic method for the purity definition and content determination of triprolidine hydrochloride.
Keywords:triprolidine hydrochloride  HPLC  purity definition  content determination  
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