化学发光免疫法与免疫放射法检测血清TSH的临床价值比较 |
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摘 要: |
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关 键 词: | 化学发光免疫法 免疫放射法 检测 血清 TSH 甲状腺机能亢进 甲状腺机能减低 |
Clinical value comparison between chemiluminescent immunoassay and immunoradiometric assay in detecting TSH in serum] |
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Authors: | Jian-ying Yu Ying Lin |
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Institution: | Department of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha 410008, China. |
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Abstract: | OBJECTIVE: To compare the clinical value between chemiluminescent immunoassay (CLIA) and immunoradiometric assay (IRMA) in detecting TSH in patients with hyperthyroidism and hypothyroidism. METHODS: The TSH levels in serums were detected by CLIA and IRMA in 112 normal persons, 120 hyperthyroidism patients and 58 hypothyroidism patients. RESULTS: CLIA was significantly correlated with IRMA (r = 0.98, P < 0.01). CLIA had higher coincidence rate than IRMA in the diagnosis of hyperthyroidism and hypothyroidism, and CLIA was more accurate and repetitive than IRMA. CONCLUSION: CLIA is more valuable than IRMA in diagnosing both hyperthyroidism and hypothyroidism. |
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