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化学发光免疫法与免疫放射法检测血清TSH的临床价值比较
摘    要:

关 键 词:化学发光免疫法  免疫放射法  检测  血清  TSH  甲状腺机能亢进  甲状腺机能减低

Clinical value comparison between chemiluminescent immunoassay and immunoradiometric assay in detecting TSH in serum]
Authors:Jian-ying Yu  Ying Lin
Institution:Department of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Abstract:OBJECTIVE: To compare the clinical value between chemiluminescent immunoassay (CLIA) and immunoradiometric assay (IRMA) in detecting TSH in patients with hyperthyroidism and hypothyroidism. METHODS: The TSH levels in serums were detected by CLIA and IRMA in 112 normal persons, 120 hyperthyroidism patients and 58 hypothyroidism patients. RESULTS: CLIA was significantly correlated with IRMA (r = 0.98, P < 0.01). CLIA had higher coincidence rate than IRMA in the diagnosis of hyperthyroidism and hypothyroidism, and CLIA was more accurate and repetitive than IRMA. CONCLUSION: CLIA is more valuable than IRMA in diagnosing both hyperthyroidism and hypothyroidism.
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