黄龙汤对鼠在体肠推进的影响

目的:探讨黄龙汤对实验鼠肠运动的影响.方法:采用肠管运动在体实验法测定小鼠排便时间及频率和肠推进运动,并与大承气汤作比较.结果:黄龙汤使排便时间加快,次数增加,便稀且不成形,能明显促进小鼠小肠推进运动,对大鼠大肠推进的直接和间接作用均明显增加.且作用强于大承气汤.结论:黄龙汤对实验动物有明显的泻下作用,作用机理可能是黄龙汤有促进在体动物肠运动的作用.

Effect of Huanglongtang on intact intestine motility in animals

OBJECTIVE To investigate the effect of Huanglongtang on small and large intestine motility in mouse and rat.METHODS The way of intact intestine motility was used to measure the time to start defecation, the frequency of defecation and intestine moved forwards.RESULTS The defecation time was moved up and the mouse small intestine motility was promoted strikingly by Huanglongtang. Effcet of direct and indirect locomotion on rat large intestine was enhanced notably, and the effect on the large intestine was superior to Dachengqitang compared with Huanglongtang.CONCLUSIONS It is suggested that Huanglongtang has an outstanding purgative action, in which mechanism may be promoting the intact intestine locomotion.