广东地区急性冠脉综合征患者中医证候特征分析

目的：开展广东地区的多中心的前瞻性的调查研究,探讨广东地区急性冠脉综合征的证候特征。方法：通过广东地区的13家分中心为期1年的病例收集,共纳入急性冠脉综合征患者109例,主要调查辨证要素及其组合的分布特征,重点探讨从急性期到亚急性期的证候演变规律。结果：本研究发现入选时辨证要素中所占比例最高的前三位分别是气虚（70.60%）、痰浊（51.40%）、血虚（31.20%）,所有的证素组合中气血两虚痰浊证为最多;入选1周后辨证要素中所占比例最高的前三位是气虚（61.50%）、痰浊（52.30%）、血瘀（34.00%）,所有的证素组合中气虚痰浊血瘀为最多;入选2周后辨证要素中所占比例最高的前三位是气虚（53.20%）、血瘀（38.50%）、痰浊（33.00%）,气虚痰浊血瘀依然是占比例最多的证型。结论：总结了广东地区急性冠脉综合征的证候特征演变规律,对临床有一定的指导意义,但其应用价值仍有待进一步的大规模临床流行病学的调查分析。

Analysis of Characteristics of TCM Syndrome of Patients with Acute Coronary Syndromes in Guangdong Area

Objective：To carry out multicenter prospective investigation and study in Guangdong region,and to explore characteristics of acute coronary syndrome syndromes in Guangdong area. Methods：Through cases collection 13 sub-center for 1 year in Guangdong area, total included 109 patients with acute coronary syndrome, mainly investigated the distribution features of the syndrome elements and their combination, the paper mainly discussed from acute to subacute phase of syndromes evolution rule. Results ： This study found that syndrome elements proportion of the top three when including respectively were qi deficiency（70.60% ） ,phlegm turbidlty（51.40% ） , blood deficiency（31.20% ） , all evidence element combinations of two qi-blood phlegm turbidity syndrome was the most;in one week af- ter differentiation factor proportion of the top three was qi deficiency（61.50% ）, phlegm turbidity（ 52.30% ） , blood stasis（ 34.00% ） , all syndrome element combinations of deficiency of phlegm turbidity and blood stasis was the most ; in 2 weeks after the dialectical factor proportion of the top three was qi deficiency （ 53.20% ） , blood stasis （ 38.50% ） , and phlegm turbidity （ 33.00% ） , qi deficiency, phlegm turbidity and blood stasis type was still the highest proportion of type. Conclusion ：The article summarizes acute coronary syndrome char- acteristics evolution rules in Guangdong area, which has certain guiding significance in clinical, but its application value remains to be further large-scale investigation and analysis of clinical epidemiology.