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PRIMARY SYSTEMIC AMYLOIDOSIS WITH SEVERE CARDIAC AMYLOIDOSIS
Authors:Yoshio Hiasa    Yoshiteru Kitahobi    Noboru Konishi    Taketo Shimoyama    Yasuhiro Sakaguchi    Asao Seki  Hiroyuki Akiyama    Akiko Kose   Akira Yoshida
Affiliation:1st Department of Pathology, Nara Medical University, Kashihara, Nara;2nd Division, Central Clinical Research Laboratory, Nissei Hospital, Osaka;2nd Department of Internal Medicine, Nissei Hospital, Osaka
Abstract:
An autopsy case of primary systemic amyloidosis with severe cardiac amyloidosis in a 75-year-old Japanese man is reported. The initial signs were dyspnea and cough, followed by general fatigue and loss of appetite. Heart failure, pleural effusion, and liver cysts were found on physiological examination. Autopsy findings were primary sytemic amyloidosis with severe diffuse cardiac amyloidosis and cardiac hypertrophy (585 g). Focal necrosis by infarction was found in the liver and spleen. The cause of amyloidosis was unknown. ACTA PATHOL. JPN. 35: 905–914, 1985.
Keywords:
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