急性缺血性脑卒中颅内、外动脉粥样硬化狭窄的相关因素

目的 研究急性缺血性脑卒中患者颅内、外动脉狭窄的分布特点,并对颅内、外动脉狭窄的危险因素进行分析.方法 对160例急性缺血性脑卒中患者进行颅内、外血管磁共振血管成像(MRA)和颈部血管超声检查,对有动脉狭窄或闭塞的患者按血管狭窄累及的部位分为单纯颅内动脉狭窄组、单纯颅外动脉狭窄组和颅内合并颅外动脉狭窄组,对颅内、外大动脉的狭窄率、分布特点和危险因素进行统计分析.结果 160例缺血性脑卒中患者中,颅内、外动脉狭窄的发生率为84.4%(135/160),其中单纯颅内动脉、颅外动脉及颅内合并颅外动脉狭窄的发生率分别为43.7%(59/135)、15.6%(21/135)和40.7%(55/135).颅内合并颅外动脉狭窄组患者的平均年龄为(69±11)岁,显著高于单纯颅内动脉狭窄组[(65±12)岁]和单纯颅外动脉狭窄组[(65±11)岁,P值均<0.05].Logistic分析显示,高血压((OR=2.543,95% CI为1.011～6.352,P=0.047)、糖尿病(OR=4.133,95% CI为1.158～14.740,P=0.029)是动脉狭窄-闭塞的独立危险因素.结论 在急性缺血性脑卒中患者中,高血压、糖尿病是颅内、外动脉狭窄的独立危险因素.

Risk factors of intracranial and extracranial atherosclerotic stenosis in patients with acute ischemic stroke

Objective To explore the distribution of the intracranial and extracranial atherosclerotic stenosis in patients with acute ischemic stroke,and to analyze the risk factors of artery stenosis.Methods Magnetic Resonance Angiography(MRA)and vascular ultrasound were performed on 160 patients with acute ischemic stroke.Based on the findings the artery stenoses were divided into intracranial group,extracranial group and intra-extra cranial group according to the location of the vascular lesion.Statistical analysis...