The prevalence of comorbid respiratory disease among COVID-19 patients,and mortality during the first wave in Japan: A nationwide survey by the Japanese Respiratory Society |
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| Institution: | 1. Division of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan;2. Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan;3. Department of Respiratory Medicine and Allergology, Kindai University Faculty of Medicine, Osaka, Japan;4. Department of Respiratory Medicine, Hokkaido University Faculty of Medicine, Sapporo, Japan;5. Department of Pulmonary Medicine, University of Tsukuba, Tsukuba, Japan;6. Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Kanagawa, Japan;7. Department of Respiratory Medicine and Clinical Allergy, Fujita Health University, Aichi, Japan;8. Department of Respiratory Medicine and Allergology, Kochi Medical School, Kochi University, Kochi, Japan |
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| Abstract: | There is a concern that persons with underlying respiratory disease may have increased susceptibility to COVID-19 and/or increased severity/mortality if infected. However, information regarding such patients during the first wave of the epidemic is lacking in Japan. We surveyed chest physicians nationwide, and collected anonymous data concerning 1444 patients.Among COVID-19 patients, the prevalence of asthma, chronic obstructive pulmonary disease (COPD), and interstitial lung diseases (ILD) was 3.4%, 4.8%, and 1.5%, respectively. Among COVID-19 patients with these 3 comorbidities, exacerbation of the comorbidity occurred in 12.2%, 18.8%, and 36.4%, respectively, and mortality (6.2% overall) was 4.1%, 13.0%, and 31.8%, respectively.The prevalence of asthma among COVID-19 patients was not higher than that for the general population, and mortality in COVID-19 patients with asthma was not higher than mortality in COVID-19 patients without underlying respiratory disease. COVID-19 patients having COPD or ILD had relatively high mortality, especially for ILD. |
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| Keywords: | Asthma COPD COVID-19 Interstitial lung disease Mortality COPD"} {"#name":"keyword" "$":{"id":"kwrd0040"} "$$":[{"#name":"text" "_":"chronic obstructive pulmonary disease COVID-19"} {"#name":"keyword" "$":{"id":"kwrd0050"} "$$":[{"#name":"text" "_":"coronavirus disease 2019 ECMO"} {"#name":"keyword" "$":{"id":"kwrd0060"} "$$":[{"#name":"text" "_":"extracorporeal membrane oxygenation ILD"} {"#name":"keyword" "$":{"id":"kwrd0070"} "$$":[{"#name":"text" "_":"interstitial lung disease Japanese Respiratory Society"} {"#name":"keyword" "$":{"id":"kwrd0080"} "$$":[{"#name":"text" "_":"JRS LPV/r"} {"#name":"keyword" "$":{"id":"kwrd0090"} "$$":[{"#name":"text" "_":"lopinavir/ritonavir MV"} {"#name":"keyword" "$":{"id":"kwrd0100"} "$$":[{"#name":"text" "_":"mechanical ventilation SARS-CoV-2"} {"#name":"keyword" "$":{"id":"kwrd0110"} "$$":[{"#name":"text" "_":"severe acute respiratory syndrome coronavirus-2 |
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