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Potential Effects of Cannabidiol as a Wake-Promoting Agent
Authors:Eric Murillo-Rodríguez  Andrea Sarro-Ramírez  Daniel Sánchez  Stephanie Mijangos-Moreno  Alma Tejeda-Padrón  Alwin Poot-Aké   Khalil Guzmán  Elda Pacheco-Pantoja  Oscar Arias-Carrión
Abstract:Over the last decades, the scientific interest in chemistry and pharmacology of cannabinoids has increased. Most attention has focused on ∆9-tetrahydrocannabinol (∆9-THC) as it is the psychoactive constituent of Cannabis sativa (C. sativa). However, in previous years, the focus of interest in the second plant constituent with non-psychotropic properties, cannabidiol (CBD) has been enhanced. Recently, several groups have investigated the pharmacological properties of CBD with significant findings; furthermore, this compound has raised promising pharmacological properties as a wake-inducing drug. In the current review, we will provide experimental evidence regarding the potential role of CBD as a wake-inducing drug.
Keywords:Dopamine   hypothalamus   marijuana   sleep   sleepiness.
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