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4组治疗消化性溃疡方案的成本-效果分析
引用本文:杨素萍,杨理会,李小鸿.4组治疗消化性溃疡方案的成本-效果分析[J].中国临床药学杂志,2002,11(5):281-283.
作者姓名:杨素萍  杨理会  李小鸿
作者单位:浙江省乐清市人民医院药剂科,乐清,325600
摘    要:目的:探讨不同的药物治疗方案对幽门螺杆菌(HP)感染的消化性溃疡疾病的成本-效果。方法:运用药物经济学成本-效果分析法对4组治疗方案即A组:奥美拉唑+阿莫西林+甲硝唑;B组:兰索拉唑+阿莫西林+甲硝唑;C组:奥美拉唑+克拉霉素+甲硝唑;D组:兰索拉唑+丽珠胃三联(枸橼酸铋钾-克拉霉素-替硝唑)进行分析评价。结果:4组方案的成本-效果比(C/E),HE消除:A9.08,B8.56,C12.05,D12.97;溃疡治愈:A8.62,B8.23,C11.44,D13.65。结论:B组为最佳治疗方案,值得推广应用。

关 键 词:消化性溃疡  治疗方案  成本-效果分析  奥美拉唑  阿莫西林  甲硝唑  兰索拉唑  克拉霉素  丽珠胃三联
文章编号:1007-4406(2002)05-0281-03

Cost-effectiveness analysis in 4 groups of the therapeutic schemes for peptic ulcer
Yang Shuping,Yang Lihui,Li Xiaohong.Cost-effectiveness analysis in 4 groups of the therapeutic schemes for peptic ulcer[J].Chinese Journal of Clinical Pharmacy,2002,11(5):281-283.
Authors:Yang Shuping  Yang Lihui  Li Xiaohong
Abstract:AIM: To explore the cost effectiveness of the various drug treatment schemes in peptic ulcer of HP infection. METHODS: Four groups treatment schemes (group A: omeprazole amoxicillin metronidazole; group B: lansoprazole amoxicillin metronidazole, group C: omeprazole clarithromycin metronidazole, group D: lansoprazole Li Zhu three stomachic drug unite) were evaluated by means of the cost effectiveness analytic methods of drug economics. RESULTS: The cost effectiveness ratio for 4 groups was HP eraduation: A 9.08, B 8.56, C 12.05, D 12.97; ulcer healing: A 8.62, B 8 23, C 11.44, D 13.65. CONCLUSION: The best treatment scheme is group B, and may be worth spreading application.
Keywords:peptic ulcer  treatment scheme  cost  effectiveness analysis
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