温度对单个人红细胞膜力学特性的即时作用

目的：探讨温度对单个红细胞膜力学性质的即时影响。 方法： 利用静态显微图像分析技术和动态显微图像分析技术，在无损、实时、在位的情况下，观察和测量不同温度下单个人红细胞的形态、大小、膜弯曲弹性模量和剪切弹性模量的变化。 结果： 红细胞的接触面积和直径随温度的升高而减小，胞膜的弯曲弹性模量和剪切弹性模量都在生理温度37 ℃时最小，而温度低于或高于37 ℃时红细胞膜的弯曲弹性模量和剪切弹性模量都增大。 结论： 红细胞在生理温度37 ℃时有最好的形态和力学变形性，便于发挥其生理功能。

Instant effects of temperature on mechanical properties of single living intact human red blood cell

AIM: To study the instant effect of circumstance temperature on mechanical properties of single living intact human red blood cell. METHODS: The shape, size, membrane bending elastic modulus and shear elastic modulus of single living intact red blood cell was determined with non-invasive, in situ, real time by employing a static micro-image analyzing and a dynamic micro-image analyzing system. RESULTS: The contact area and diameter of red blood cells were decreased as the temperature increased from 35 ℃ to 43 ℃. The membrane bending elastic modulus and shear elastic modulus of single living intact red blood cell were the least at physiological temperature 37 ℃. CONCLUSION: Red blood cells are easy to carry out their physiological functions such as carrying oxygen to all of the body with the best shape and mechanical deformation at 37 ℃.