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Circulating Tumor Cells in Metastatic Breast Cancer:Monitoring Response to Chemotherapy and Predicting Progression-Free Survival
作者单位:Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education);Department of Medical Oncology, Peking University School of Oncology,Beijing Cancer Hospital & Institute Beijing 100142, China
摘    要:


Circulating tumor cells in metastatic breast cancer: Monitoring response to chemotherapy and predicting progression-free survival
Jian-ping Cheng,Ying Yan,Xiang-yi Wang,Yuan-li Lu,Yan-hua Yuan,Xiao-li Wang,Jun Jia,Jun Ren. Circulating tumor cells in metastatic breast cancer: Monitoring response to chemotherapy and predicting progression-free survival[J]. Chinese Journal of Cancer Research, 2010, 22(3): 201-210. DOI: 10.1007/s11670-010-0201-x
Authors:Jian-ping Cheng  Ying Yan  Xiang-yi Wang  Yuan-li Lu  Yan-hua Yuan  Xiao-li Wang  Jun Jia  Jun Ren
Affiliation:1.Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education); Department of Medical Oncology,Peking University School of Oncology, Beijing Cancer Hospital & Institute,Beijing,China
Abstract:

Objective  

The purpose of this study is to explore RT-PCR method to set up the examination platform for detecting circulating tumor cells (CTC) in peripheral blood from metastatic breast cancer patients. The primary endpoint is to find out the correlation of existence of CTC with clinical responses and progression-free survival (PFS).
Keywords:Breast cancer   Circulating tumor cells   CK19   RT-PCR   ELISA
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