| 慢性活动性EB病毒感染的研究进展 |
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| 引用本文： | 段红梅,谢正德,申昆玲. 慢性活动性EB病毒感染的研究进展[J]. 临床儿科杂志, 2007, 25(2): 153-156 |
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| 作者姓名： | 段红梅 谢正德 申昆玲 |
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| 作者单位： | 首都医科大学附属北京儿童医院病毒室,北京,100045;首都医科大学附属北京儿童医院病毒室,北京,100045;首都医科大学附属北京儿童医院病毒室,北京,100045 |
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| 摘 要： | 慢性活动性EB病毒感染（Chmnic active EBV infection，CAEBV）是一种少见的发生在无明确免疫缺陷个体的综合征，临床表现多种多样，其病理改变几乎可涉及到各个器官。主要表现为EBV感染后出现慢性或复发性传单样症状，伴随EBV抗体的异常改变或病毒载量的升高，病程中可出现严重的或致死的并发症。文章就其发病机制、临床表现、实验室检查及诊治方案进展作一介绍，以提高临床对慢性活动性EBV的诊治水平。
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| 关 键 词： | EB病毒 慢性活动性 感染 诊断 治疗 |
| 文章编号： | 1000-3606（2007）02-153-04 |
| 收稿时间： | 2006-03-15 |
| 修稿时间： | 2006-03-15 |
Advances in research on chronic active Epstein-Barr virus infection |
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| DUAN Hong-mei,Xie Zhen-de,SHEN Kun-ling. Advances in research on chronic active Epstein-Barr virus infection[J]. The Journal of Clinical Pediatrics, 2007, 25(2): 153-156 |
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| Authors: | DUAN Hong-mei Xie Zhen-de SHEN Kun-ling |
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| Abstract: | Chronic active Epstein -Barr virus (CAEBV) infection is an uncommon outcome of Epstein-Barr virus infection and may present as severe or fulminant syndrome with high-mortality. The clinical manifestation of CAEBVI is diverse and various organs may be involved. It was characterized by chronic or recurrent infectious mononucleosis-like symptoms persisting over a long time and by an unusual pattern of anti-EBV antibodies or high viral load. Although it occurs in immunocompetent individuals, subtle underlying immunodeficiency may exist in patients with CAEBV. This review focuses on CAEBV regarding its pathogenic mechanisms, clinical manifestation, diagnosis, and treatment strategies. |
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| Keywords: | Epstein- Barr virus chronic active infection diagnosis treatment |
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