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Myocarditis following AstraZeneca (an adenovirus vector vaccine) COVID‐19 vaccination: A case report
Authors:Shakiba Hassanzadeh  Somayeh Sadeghi  Ahmad Mirdamadi  Alireza Nematollahi
Affiliation:1. Division of Pathology, Nickan Research Institute, Isfahan Iran ; 2. Acquired Immunodeficiency Research Center, Isfahan University of Medical Sciences, Isfahan Iran ; 3. Department of Cardiology, Islamic Azad University, Najafabad Branch, Najafabad, Isfahan Iran ; 4. Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan Iran
Abstract:Coronavirus disease‐19 (COVID‐19) vaccines are massively administered globally and some adverse events, such as myocarditis, are being reported. Most of the reported cases of post‐vaccination myocarditis have occurred following mRNA vaccinations. However, there have also been recent reports of myocarditis following adenovirus vector vaccinations. We present a case of a 32‐year‐old female patient who developed myocarditis following the administration of the first dose of the AstraZeneca vaccine. The patient developed inappropriate exertional tachycardia and exertional dyspnea from Day 3 and was diagnosed with myocarditis by subsequent echocardiography about 3 months later. We are unable to confirm a direct association between myocarditis and AstraZeneca vaccination. However, we would like to increase awareness regarding the possibility of developing myocarditis following AstraZeneca vaccination.
Keywords:AstraZeneca‐  associated myocarditis, COVID‐  19 vaccination‐  associated myocarditis, mRNA COVID‐  19 vaccines, myocarditis, viral vector vaccines
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