| Abstract: | Serum from a 75-year-old man with lymphoproliferative disease was found to contain a persistent cold agglutinin meeting most of the characteristics of examples of anti-Gd reported previously. It differed, however, in that it contained IgG and IgM components and its reactivity was not inhibited by sialyllactose. A search of random serums containing cold agglutinins was undertaken to determine the incidence of antibodies to antigens dependent on N-acetylneuraminic acid. Two further examples were found in 47 serums containing cold agglutinins. One of these also demonstrated a Gd or "Gd-like" specificity. The other appeared to be an anti-Pr. |
