| 急性心肌梗死患者行冠状动脉介入治疗后应激激素与血糖变化及其对预后的影响 |
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| 引用本文： | 李英梅,丘洪,汪蔚青,杨伟,刘宗军,方平,于宏梅,王大英,沈峻,汪志华,孟莉,金惠根.急性心肌梗死患者行冠状动脉介入治疗后应激激素与血糖变化及其对预后的影响[J].中国实用内科杂志,2010(1). |
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| 作者姓名： | 李英梅 丘洪 汪蔚青 杨伟 刘宗军 方平 于宏梅 王大英 沈峻 汪志华 孟莉 金惠根 |
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| 作者单位： | 上海中医药大学附属普陀医院心内科;上海中医药大学附属普陀医院老年科; |
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| 基金项目： | 上海市卫生局青年基金(2006Y063) |
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| 摘 要： | 目的探讨急性心肌梗死(AMI)患者行冠状动脉介入治疗(PCI)后应激激素与血糖变化及其对预后的影响。方法对上海中医药大学附属普陀医院心内科2006年10月至2009年5月收治的115例非糖尿病AMI患者入院即刻血糖进行测定,将其分为无应激性高血糖组68例(A组)和应激性高血糖组(随机血糖≥7.8mmol/L)47例(B组),对比分析两组的临床资料和应激激素变化及30d内心力衰竭、再发心肌梗死、梗死后心绞痛、严重心律失常及心血管死亡情况。结果应激性高血糖的发生率为40.87%;B组应激激素(皮质醇、生长激素、胰高血糖素、ACTH)显著高于A组(P0.01),而B组胰岛素显著低于A组(P0.01);AMI急性期B组心力衰竭、再发心肌梗死、梗死后心绞痛、严重心律失常及心血管死亡情况均显著高于A组(P0.05)。B组左心室射血分数(49.97±7.21)%]显著低于A组(54.03±6.34)%](P0.05)。结论入院血糖与应激激素异常增高和AMI患者PCI术后30d内预后较差相关。
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| 关 键 词： | 心肌梗死 应激 血糖 激素 |
Alteration of stress hormones and glucose levels after percutaneous coronary intervention in patients with acute myocardial infarction and its influence on prognosis |
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| LI Ying-mei,QIU Hong,WANG Wei-qing,YANG Wei,LIU Zong-jun,FANG Ping,YU Hong-mei,WANG Da-ying,SHEN Jun,WANG Zhi-hua,MENG Li,JIN Hui-gen.Alteration of stress hormones and glucose levels after percutaneous coronary intervention in patients with acute myocardial infarction and its influence on prognosis[J].Chinese Journal of Practical Internal Medicine,2010(1). |
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| Authors: | LI Ying-mei QIU Hong WANG Wei-qing YANG Wei LIU Zong-jun FANG Ping YU Hong-mei WANG Da-ying SHEN Jun WANG Zhi-hua MENG Li JIN Hui-gen |
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| Institution: | LI Ying-mei,QIU Hong,WANG Wei-qing,YANG Wei,LIU Zong-jun,FANG Ping,YU Hong-mei,WANG Da-ying,SHEN Jun,WANG Zhi-hua,MENG Li,JIN Hui-gen.Department of Cardiology,Shanghai Putuo Hospital,University of Traditional Chinese Medicine,Shanghai 200062,China |
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| Abstract: | Objective Acute myocardial infarction(AMI)can lead to a series of neuroendocrine changes and results in severe stress,causes critical complications.This study investigates the alteration of stress hormones and glucose levels and its prognostic value after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction.Methods A total of 115 non-diabetics patients with ST elevation MI (STEMI) receiving PCI were divided into 2 groups according to Serum Glucose(SG)levels at admission:Grou... |
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| Keywords: | myocardial infarction stress glucose hormone |
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