急性心肌梗死患者心律震荡的研究

目的　研究新的心电学指标——心律震荡 (heart rate turbulence,HRT)在急性心肌梗死 (AMI)患者中的变化 ,并与传统指标——心率变异性 (HRV)进行比较 ,分析二者的相关性。方法　选择 5 0名 AMI患者和 5 0例对照者行 2 4 h动态心电图 (Holter)检查 ,计算 HRT的两个参数震荡初始 (TO)和震荡斜率 (TS) ,并对TO、TS与 HRV进行对比分析。结果　 AMI组 TS明显减弱 ,与对照组比较差异有显著性 (P<0 .0 1) ;而 TO在AMI组和对照组差异无显著性 (P>0 .0 5 ) ;TO、TS和 HRV无明显相关性 (P>0 .0 5 )。结论　 AMI组患者 TS减低 ,HRT减弱 ,HRT可能成为评价急性心肌梗死患者自主神经功能状态、预测恶性心律失常和心源性猝死独立的新指标

Study on the heart rate turbulence in acute myocardial infarction

Objective To study the changes of new electrocardiologic index——heart rate turbulence (HRT) in acute myocardial infarction (AMI),compare with conventional index——heart rate variability (HRV) and analyse the correlation of them.Methods Fifty patients with AMI and fifty control subjects served as the study population.They were examined by 24 h Holter monitoring.The computer analysed and computed two factors——trubulence onset (TO) and turbulence slope (TS) of HRT,and contrasted TO and TS with HRV.Results There is statistical difference between two guoups,that is the TS of AMI guoup is significantly lower than that of the later group (P<0.01).There is no correlation between TO,TS and HRV (P>05).Conclusion TS decreases dramatically in AMI patients,and HRT is weaken.Therefore HRT maybe becomes a new independent index to evaluate the cardiac autonomic status and to forecast the malignant arrhythmia and sudden cardiac death.