| 艰难梭菌毒素A＆B测定在医院腹泻患者中的应用 |
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| 引用本文： | 李文丽,简子娟,刘文恩,刘清霞. 艰难梭菌毒素A＆B测定在医院腹泻患者中的应用[J]. 中国感染控制杂志, 2010, 9(4): 261-263,237 |
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| 作者姓名： | 李文丽 简子娟 刘文恩 刘清霞 |
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| 作者单位： | 中南大学湘雅医院,湖南长沙,410008 |
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| 摘 要： | 目的探讨艰难梭菌毒素AB测定在医院腹泻患者中的应用价值。方法采用VIDAS艰难梭菌AB毒素检测试剂对某院47例住院的腹泻患者粪便标本进行毒素检测,并结合细菌常规培养、临床资料及治疗进行综合分析。结果 47例腹泻患者中,7例(14.89%)艰难梭菌毒素检测阳性,此7例阳性结果均与临床诊断和/或治疗相符。结论该院艰难梭菌感染形势较为严峻,VIDAS艰难梭菌AB毒素检测可提供简单、准确、快速的检测结果,值得推广应用。
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| 关 键 词： | 腹泻 艰难梭菌 医院感染 毒素 |
The application of toxin A & B (CDAB) assay in diarrheal inpatients |
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| LI Wen-li,JIAN Zi-juan,LIU Wen-en,LIU Qing-xia. The application of toxin A & B (CDAB) assay in diarrheal inpatients[J]. Chinese Journal of Infection Control, 2010, 9(4): 261-263,237 |
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| Authors: | LI Wen-li JIAN Zi-juan LIU Wen-en LIU Qing-xia |
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| Affiliation: | ( Xiangya Hospital, Central South University, Changsha 410008, China) |
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| Abstract: | Objective To study the clinical value of toxin A ＆ B （CDAB） assay in diarrheal inpatients. Methods Faecal specimens from 47 inpatients with diarrhea were tested by the VIDAS Clostridiurn difficile （C. difficile） toxin A＆ B （CDAB） assay, and the results were analyzed together with the bacterial routine culture, clinical data and treatment. Results Among 47 cases of diarrhea patients, 7 （14. 89%） were VIDAS CDAB＋ , the results conformed with clinical diagnosis and/or treatment. Conclusion The situation of C. difficile infection in this hospital is severe. VIDAS C. difficile Toxin A ＆ B （CDAB） assay is simple, rapid and accurate, which is recommended to be used clinically. |
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| Keywords: | diarrhea Clostridiumdifficile nosocomial infection toxins |
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