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Synthesis of 2‐d‐acrylamide
Authors:Alexey V Salin  Rashid Z Musin
Institution:1. A.M. Butlerov Institute of Chemistry, Kazan Federal University, Kazan, Russia;2. A.E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center of Russian Academy of Sciences, Kazan, Russia
Abstract:2‐d‐Acrylamide was synthesized via the 2‐step procedure starting from acrylonitrile and deuterium oxide. This procedure affords 2‐d‐acrylamide in 99.9% chemical purity and 98.4% isotopic enrichment.
Keywords:deuterium‐labeled acrylamide  deuterium‐labeled acrylonitrile  electron‐deficient alkenes  hydration
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