523例变态反应性皮肤病患者过敏原检测结果分析

目的：探讨变态反应性皮肤病患者常见过敏原的分布特征。方法：对本院皮肤科门诊523例变态反应性皮肤病患者按荨麻疹组（322例）和皮炎、湿疹组（201例）进行分类;应用德国MORA-SUPER生物共振治疗仪对患者进行吸入、食入、其他变应原检测,进行相关统计学分析。结果：过敏原阳性率荨麻疹组为87.89%,皮炎、湿疹组为83.08%;从过敏原分布特征来看,以多种、多组物质过敏的患者为多;皮炎、湿疹组内少年组与中老年组之间阳性率差异较大。荨麻疹组前十位过敏原是：螨和昆虫（占54.97%）、霉菌（占49.38%）、海鲜类（占31.37%）、组胺（占20.50%）、酵母（占14.91%）、食用防腐剂（占14.29%）、抗氧化剂（占13.66%）、蛋黄（占12.11%）、甜味剂（占9.01%）、香料和药草（占7.45%）;皮炎、湿疹组前十位过敏原是：螨和昆虫（占55.22%）、霉菌（占36.82%）、海鲜类（占31.84）、重金属（占15.92%）、抗氧化剂（占13.43%）、组胺（占12.44%）、食用防腐剂（占11.44%）、酵母（占8.46%）、谷类（占7.96%）、蛋黄（占7.46%）、广泛环境毒素（占7.46%）。结论：变态反应性皮肤病患者的过敏原分布具有一定特征，可为本地区过敏性疾病的预防和i台疗提供一定依据。

Analysis of the allergens in 523 patients with allergic diseases

Objective：To explore the distributional characteristics of allergens in patients with allergic dermatosis.Methods：Five hundred and twenty three patients with allergic dermatosis were enrolled into this observation,including 322 cases of urticaria and 201 cases of dermatitis /eczema.Three kinds of allergens（inhalation,ingestion and other allergens groups） were detected by Mora s device.Results：Allergens were found in 87.89% of the urticaria patients and 83.08% of the dermatitis/eczema patients.Most patients displayed sensitivity to more than one kind of allergen. In the dermatitis/eczema, juvenile group had a much higher positive rate than that in middle-old aged one. The first 10 allergens found in urticaria group were mites＋insect （54.97%）, moulds （49.38%）, fish （31.37%）, histamine （20.50%）, yeast （14.91%）, preserving agents （14.29%）, an-tioxidants （13.66%）, egg yoke （12.11%）, sweetening agents （9.01%）, spices and Herbs （7.45%） and in dermatitis /eczema group those were mites＋insect （55.22%）, moulds （36.82%）, fish （31.84）, heavy metals （15.92%）~ antioxidants （13.43%）, histamine （12.44%）, preserving agents （11.44%）~ yeast （8.46%）, cereals （7.96%）, egg yoke （7.46%） and extensive environmetal toxin. Conclusion： The allergens found in the patients with allergic dermatosis in this paper may clew the specificity of WenZhou region and provide a reference for the prevention and therapy of the diseases.