化红降纤汤对高血压患者血液流变学的影响

目的 观察化红降纤汤对高血压患者血液流变学和血浆纤维蛋白原（FIB）的影响。方法高血压患者100例，随机分为治疗组50例，对照组50例，分别用化红降纤汤和阿司匹林治疗8周，检测治疗前后两组血液流变学和FIB等指标。结果治疗组治疗后全血黏度低切、红细胞变形指数、红细胞聚集指数差异有统计学意义（P〈0．01），并优于对照组（P〈0．05），对照组血小板聚集率的改善优于治疗组，但无统计学意义。结论化红降纤汤可有效地降低高血压患者血黏度，改善机体红细胞和纤溶功能，有益于动脉硬化的防治及减少血栓性事件的发生。

Effect of Huahongjiangxian decoction on hemorheology in patients with hypertension

Objective To observe the effect of Huahongjiangxiantang on hemorheology and plasma fibrinogen (FIB).Methods 100 patients with hypertension were randomly divided into two groups:the treatment group ( n=50) which were treated with Huahongjiangxian-tang,and the control group( n=50)were treated with Aspirin.Hemorheology and plasma fibrin were detected before and after treatment for 8 weeks.Results After 8 weeks treatment,there were significant depressions in whole blood viscosity(low shear rate),RBC deformability index and RBC aggregation index( P＜0.01 ),and better than the control group( P ＜0.05 ).There were significant changes in whole blood viscosity ( high shear rate),plasma viscosity,RBC rigidity index and plasma fibrin ( P ＜ 0.05 ).A number of indicators declined significantly in control group ( P ＜ 0.05 );The rate of platelet aggregation to improve the situation in the control group was better than that of the treatment group,but there was no statistical significance.Conclusion Huahongjiangxiantang can effectively reduce blood viscosity in patients with hypertension and improve the body's red blood cell function and fibrinolysis,benefit to the prevention and treatment of atherosclerosis and reduce the occurrence of thrombotic events.