Comparison of a human T-cell lymphotropic virus type I strain from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis with a prototype human T-cell lymphotropic virus type I. |
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| Authors: | P S Sarin P Rodgers-Johnson D K Sun A H Thornton O S Morgan W N Gibbs C Mora G McKhann nd D C Gajdusek C J Gibbs Jr |
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| Affiliation: | Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, MD 20892. |
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| Abstract: | The isolation and characterization of a human T-cell lymphotropic retrovirus related to human T-cell lymphotropic virus type I (HTLV-I) from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis is described. The virus isolate is a typical type C retrovirus as seen by electron microscopy and is related to prototype HTLV-I isolated from patients with adult T-cell leukemia but is not identical to this prototype HTLV-I as seen by restriction enzyme mapping. |
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