生物可降解聚合物载药纳米粒的制备与应用

作为一类极富发展和应用前景的药物载体控释系统,生物可降解聚合物纳米粒不但能最终被机体分解而不会产生严重的累积和毒副效应,还具有十分明显的药物缓释效果。本文从生物可降解聚合物纳米粒的材料、制备方法,以及药物纳米控释系统在医学中的应用等几个方面,综述了生物可降解聚合物载药纳米粒的研究现状及其进展。

Preparation And Application of Biodegradable Polymeric rug-loaded Nanoparticles

As a controlled drug carrier delivery system with extremely good prospect,biodegradble polymeric nanoparticles could not only be decomposed by body without any harmful accumulations and side effects,but also have an obvious delayed release effect.The authors have reviewed the current research situation and progress of biodegradable polymeric drug-loaded nanoparticles from such aspects as the materials,preparation methods and the applications of nano-controlled drug deliver system in medicine.