The effect of localized injection of adjuvant material on the draining lymph node: II. Circulating lymphocytes

The stimulation of a draining lymph node by the injection of a substance possessing adjuvanticity leads to a marked increase in the influx of lymphocytes into the node. The influx of cells has been followed in experimental mice injected intravenously with ⁵¹Cr-labelled normal mesenteric lymph node cells. The increase in size of the draining node is not due to an increased blood volume.