祛脂愈肝颗粒治疗非酒精性脂肪肝临床研究

目的:探讨祛脂愈肝颗粒对非酒精性脂肪肝患者胰岛素抵抗的干预效应。方法:将160例非酒精性脂肪肝病患者随机分为4组,每组40例(A组:空白组;B组:东宝肝泰组;C组:二甲双胍组;D组:祛脂愈肝颗粒组)。4组均以3个月为1个疗程,2个疗程后检测肝功能、血脂、葡萄糖输注率等相关指标,并进行统计分析。结果:4组治疗后与治疗前的肝功能、血脂、葡萄糖输注率等相关指标比较,差异均有统计学意义(P0.05);治疗后组间比较,祛脂愈肝颗粒组各相关数据均优于其他3组,差异有统计学意义(P0.05)。结论:祛脂愈肝颗粒可以有效干预非酒精性脂肪肝患者的胰岛素抵抗。

Clinical study on treatment of non-alcohnlic fatty liver disease by Quzhi Yugan Granule

Objectives: To investigate the intervention effect of Quzhiyugan Granule to insulin resistance of non-alcoholic fatty liver disease patients.Methods: To divide 160 non-alcoholic fatty liver disease patients into four sample-groups randomly,40 patients each sample-group(Group A: blank control group;Group B: Dongbaogantai group;Group C: metformin hydrochloride group;Group D: Quzhiyugan Granule group).To test the related medical indexes(liver function,blood lipid,Glucose infusion rate,etc.) after two courses of treatment(three months as one course of treatment) and analyze the results.Results: Comparison results of medical indexes have significant difference for all the four sample-groups before and after two courses of treatment(P<0.05).The comparison result among sample-groups suggests that the medical indexes of Group D are superior to other three sample-groups.And have significant difference(P<0.05).Conclusion: The intervention effect of Quzhiyugan Granule to insulin resistance of non-alcoholic fatty liver disease patient is significant.