| 脉冲电刺激颈舌咽神经对大鼠的电刺激反应性和电致惊厥阈的影响 |
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| 引用本文： | 张舒岩,李树蕾,杨立彬,张现娥.脉冲电刺激颈舌咽神经对大鼠的电刺激反应性和电致惊厥阈的影响[J].吉林大学学报(医学版),2011,0(5):848-850. |
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| 作者姓名： | 张舒岩 李树蕾 杨立彬 张现娥 |
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| 作者单位： | 吉林大学第一医院急救医学科,吉林长春,130021;吉林大学白求恩医学院组织学与胚胎学教研室,吉林长春,130021;吉林大学第一医院儿科,吉林长春,130021 |
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| 基金项目： | 吉林省教育厅科研基金课题 |
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| 摘 要： | 目的：观察颈舌咽神经脉冲电刺激对大鼠的电刺激反应性和电致惊厥阈的影响，阐明脉冲电刺激颈舌咽神经抗大鼠惊厥的有效性。方法：30只成年Wistar大鼠随机分为对照组、颈迷走神经电刺激组和颈舌咽神经电刺激观察组，每组各10只。对照组只行左侧颈部切开消毒处理，颈迷走神经电刺激组行左颈部迷走神经分离后脉冲电刺激，颈舌咽神经电刺激...
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| 关 键 词： | 惊厥 舌咽神经 迷走神经 大鼠，Wistar 电刺激 |
| 收稿时间： | 2011-06-12 |
Effects of electric pulse stimulation on cervical glossopharyngeal nerve on reactivity and convulsive threshold to electrostimulation in rats |
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| ZHANG Shu-yan,LI Shu-lei,YANG Li-bin,ZHANG Xian-e.Effects of electric pulse stimulation on cervical glossopharyngeal nerve on reactivity and convulsive threshold to electrostimulation in rats[J].Journal of Jilin University: Med Ed,2011,0(5):848-850. |
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| Authors: | ZHANG Shu-yan LI Shu-lei YANG Li-bin ZHANG Xian-e |
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| Institution: | 1.Department of Emergency Medicine,First Hospital,Jilin University,Changchun 130021,China;2.Department of Histology and Embryology, Norman Bethune College of Medicine, Jilin University,Changchun 130021,China;3. Department of Pediatrics,First Hospital,Jilin University,Changchun 130021,China |
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| Abstract: | Objective To observe the effects of electric pulse stimulation on cervical glossopharyngeal nerve on the reactivity and convulsive threshold in rat and to identify its efficiency against rat convulsion.Methods 30 rats were randomly divided into control group(n=10),cervical vagus nerve group(n=10) and cervical glossopharyngeal nerve group(n=10).The skin covering the left cervical parts were cut open and sterilized of rats in control group.The left cervical vagus/glossopharyngeal nerve was separated in vagus/glossopharyngeal nerve group respectively,then stimulated with electric pulse stimulation.The reactivity and convulsive threshold to electrostimulation in rats were recorded when the bilateral ears of the animals from different groups were stimulated by electrostimulation.Results The smallest voltages causing braying,tetania and clonus in rats were remarkably enhanced in cervical glossopharyngeal group compared with control group(P<0.01).However,there was no significant difference of the smallest voltages when compared with cervical vagus group(P>0.05).Conclusion Electric pulse stimulation on cervical glossopharyngeal nerve may play a role in convulation control because it effectively enhances the reactivity and convulsive threshold to electrostimulation in rats. |
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| Keywords: | convulsion glossopharyngeal nerve vagus nerve rats Wistar electric stimulation |
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