新疆农牧民静坐行为与心血管病风险的相关性研究

目的 探讨新疆农牧民静坐行为与心血管病风险的关系，为农牧民心血管病的防控提供依据。方法 2018年6月—2019年4月，完成新疆自然人群队列的基线调查，对其中农牧民的人口学信息、体力活动等进行分析，应用Framingham风险评分计算农牧民心血管病发生风险，并采用logistic回归模型，分析不同静坐行为与心血管病风险的关系；研究腰围和BMI的中介作用。结果 纳入农牧民12 528人，将静坐行为分为视屏静坐、阅读静坐和休闲娱乐静坐。经文化程度、地区、腹型肥胖、饮酒校正后，与总静坐时间<2h/d者相比，2～<3 h/d者和≥3 h/d者心血管病风险分别增加16.8%(OR=1.168,95%CI:1.003～1.359)和40.1%(OR=1.401,95%CI:1.201～1.634)。视屏静坐时间≥4 h/d者是心血管病风险的危险因素(OR=1.838,95%CI:1.346～2.509)；阅读静坐时间≥2 h/d是心血管病风险的保护因素(OR=0.526,95%CI:0.420～0.660)。未发现休闲娱乐静坐时间与心血管病风险的相关性(χ²=0....

Correlation between sedentary behavior and cardiovascular disease risk among Xinjiang farmers and herdsmen

Objective To explore the relationship between sedentary behavior and cardiovascular disease risk in Xinjiang farmers and herdsmen, and to provide reference for the prevention and control of cardiovascular disease in farmers and herdsmen. Methods From June 2018 to April 2019, a baseline survey of a natural population cohort in Xinjiang was completed, in which the demographic information and physical activity of farmers and herdsmen were analyzed. The risk of cardiovascular disease among farmers and herdsmen was calculated by applying the Framingham risk score, and the relationship between different sedentary behaviors and the risk of cardiovascular disease was analyzed using logistic regression models. The mediating role of waist circumference and BMI was investigated. Results In total 12 528 farmers and herdsmen were included, and the sedentary behavior was divided into sedentary screen watching, sedentary reading, and sedentary recreation. After correction for literacy, region, abdominal obesity, and alcohol consumption, cardiovascular disease risk was increased by 16.8% (OR=1.168, 95%CI: 1.003-1.359) and 40.1% (OR=1.401, 95%CI: 1.201-1.634) for those with sedentary time of 2 to <3 h/d and ≥3 h/d, respectively, compared with those with total sedentary time <2 h/d. Sedentary screen watching time ≥4 h/d was a risk factor for cardiovascular disease (OR=1.838, 95%CI: 1.346-2.509). Sedentary reading time ≥2 h/d was a protective factor for cardiovascular disease (OR=0.526, 95%CI: 0.420-0.660). No association was found between sedentary recreation time and cardiovascular disease risk (χ2=0.509, P=0.476). Both total sedentary time and sedentary screen watching time could influence cardiovascular disease risk through waist circumference, with mediating effects of 0.008 (95%CI: 0.001-0.004) and 0.018 (95%CI: 0.002-0.005), respectively. No mediating effect of BMI was found. Conclusion More total sedentary time and prolonged screen watching time increase the risk of cardiovascular disease in farmers and herdsmen, and lifestyle interventions should be enhanced while reducing waist circumference to decrease the risk of cardiovascular disease in farmers and herdsmen.