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Oral abnormalities in an Iranian newborn population
Affiliation:1. Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China;2. Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA;3. Department of Periodontics, College of Dentistry, Graduate College, UIC Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA;4. Department of Medicine, Tumor Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510060, China;5. Department of Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL 60612, USA;1. Department of Oral & Maxillofacial-Head & Neck Oncology, Ninth People''s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research Center of Stomatology, Shanghai 200011, China;2. Department of Oral & Maxillofacial-Head & Neck Oncology, Shanghai Fengcheng Hospital, Fengxian District, Shanghai 201400, China;3. Department of Stomatology, Shanghai East Hospital, Tongji University, Shanghai 200120, China;1. Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia;2. Community Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia;3. Department of Dental Biomaterials Research and Development, College of Dentistry, King Saud University, Riyadh, Saudi Arabia
Abstract:ObjectiveThe prevalence of oral findings in newborn infants in Iran is not known, as only isolated case reports have been published. We determined the prevalence of intraoral findings in a group of newborns and assessed the relationship between these findings and maternal systemic and gestational medical complications during pregnancy and parental consanguinity.Study designA total of 995 newborn children were examined in Hafiz Hospital, Shiraz, Iran. Oral cysts, ankyloglossia, an attached upper midline frenum, and other medical diagnoses at birth were investigated. Medical information for each child and parent was recorded via a standard questionnaire. The data were analyzed using the Pearson χ2 test (P < 0.05).ResultsThe most common findings were oral cysts (15%). There were significant relationships between oral cyst prevalence and parental consanguinity (P = 0.009) and between the presence of at least one finding and medication consumption during pregnancy (P = 0.04).ConclusionsSome 32.3% of the neonates examined had at least one oral finding within 3 days of birth, of which the most common was oral cyst. Parental consanguinity and drug intake during pregnancy were correlated with the occurrence of oral findings.
Keywords:Oral cysts  Consanguinity  Medication consumption  Neonate
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