FDG-PET/CT in staging of clear cell odontogenic carcinoma |
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| Institution: | 1. Faculty of Oral and Dental Medicine, Cairo University, Heliopolis, Cairo, Egypt;2. Maxillofacial Surgery Department, Ahmed Maher Teaching Hospital, Cairo, Egypt;1. The Research Institute of Stomatology, Nanjing Medical University, Nanjing, China;2. Department of Oral and Maxillofacial Surgery, Stomatological Hospital of Jiangsu Province, Nanjing, China;3. Department of Orthodontics, Nanjing Maternity and Child Health Care Hospital, Nanjing, China;4. Department of Prosthodontics and Implants, Jiangsu Provincial Stomatology Hospital, Stomatological Hospital of Jiangsu Province, Nanjing, China;5. Department of Stomatology, Gaoyou People''s Hospital, Gaoyou, Jiangsu Province, China;6. Department of Radiology, Stomatological Hospital of Jiangsu Province, Nanjing, China;1. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cukurova University, Adana, Turkey;2. Department of Oral and Maxillofacial Surgery, Paracelsus Medical University, Salzburg, Austria;3. Orthopedics, Privat Hospital Maria Hilf, Klagenfurt, Austria;4. Department of Histology, Faculty of Medicine, Cukurova University, Adana, Turkey |
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| Abstract: | Clear cell odontogenic carcinoma (CCOC) is a rare neoplasm; only 75 cases have been reported in the English language literature. They have a tendency for recurrence and a capacity to metastasize. There is very little known regarding the metabolic features of this tumour or the utility of fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scans in the staging and follow-up of these tumours. We present two cases of CCOC with their relevant FDG-PET/CT scan findings. The first patient had primary CCOC of the mandible that was FDG-avid, and the other had recurrence of CCOC of the anterior mandible and superomedial orbit that was not FDG-avid. FDG uptake in CCOC appears to be variable. Although FDG-PET/CT is useful in other head and neck cancers and has benefits compared to other imaging modalities, further studies are needed to investigate the sensitivity of FDG-PET/CT in CCOC. |
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