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Kleine-Levin Syndrome: A Case Report and Review of Literature
Affiliation:1. Department of Psychiatry and Sleep Clinic, Himalayan Institute of Medical Sciences, Doiwala, Dehradun, India;2. Department of Radiology, Himalayan Institute of Medical Sciences, Doiwala, Dehradun, India
Abstract:BackgroundKleine-Levin syndrome presents with recurrent hypersomnia along with a number of other neuropsychiatric features, of which hyperorality has not been described frequently.MethodWe report a male adolescent who presented with recurrent hypersomnia, hypersexuality, and hyperorality. Magnetic resonance imaging of the brain and overnight polysomnography followed by a multiple sleep latency tests were ordered. Excessive daytime sleepiness was assessed with the Epworth Sleepiness Scale.ResultsMagnetic resonance imaging of the brain did not reveal any abnormality. Overnight video-synchronized polysomnography and multiple sleep latency tests ruled out narcolepsy. Epworth Sleepiness Scale score at baseline was 22. He was prescribed lithium carbonate 300 mg twice a day. The symptoms improved within a week after starting lithium carbonate therapy.ConclusionKleine-Levin syndrome may present with hyperorality, and our patient responded well to lithium carbonate therapy.
Keywords:Kleine-Levin syndrome  recurrent hypersomnia  adolescent  lithium
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