| 依达拉奉分子印迹聚合物的制备及选择吸附性研究 |
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| 引用本文： | 蒲家志,郭春艳.依达拉奉分子印迹聚合物的制备及选择吸附性研究[J].遵义医学院学报,2008,31(5). |
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| 作者姓名： | 蒲家志 郭春艳 |
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| 作者单位： | 1. 遵义医学院,药学系,贵州,遵义,563003
2. 重庆市药友制药有限责任公司,重庆,400715 |
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| 基金项目： | 贵州省科学基金资助课题;黔基合计号:(2003)3009号
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| 摘 要： | 目的以依达拉奉(Edaravone)为模板分子,合成依达拉奉分子印迹聚合物(MIP)。方法研究不同功能单体对依达拉奉分子印迹聚合物的影响,并通过Scatchard方程研究依达拉奉分子印迹聚合物选择吸附特性。结果以甲基丙烯酸(MAA)为功能单体合成的分子聚合物具有较高的选择性。结论依达拉奉分子印迹聚合物有望用于临床对依达拉奉的富集与检测。
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| 关 键 词： | 依达拉奉 制备 分子印迹聚合物 |
The Sythesis and selective Characteristics of Molecularly Imprinted Polymers for Edaravone |
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| PU Jia-zhi,GUO Chun-yan.The Sythesis and selective Characteristics of Molecularly Imprinted Polymers for Edaravone[J].Acta Academiae Medicine Zunyi,2008,31(5). |
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| Authors: | PU Jia-zhi GUO Chun-yan |
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| Institution: | PU Jia-zhe,GUO Chun-yan(Department of Chemistry,Zunyi Medical College,Zunyi Guizhou 563003,China) |
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| Abstract: | Objective To synthesize a molecularly imprinted polymer with Edaravone as the template.Methods Study on effect on the imprinted polymer synthesized with different functional monomers and selectivity characteristics of the template polmer evaluated by scatchard equation.Results The polymer taking MAA as functional monomer obtained higher selectivity for Edaravone.Conclusions Molecular imprinting polymer will exhibit practical utility for enrichment and determination of trace Edaravone. |
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| Keywords: | Edaravone sythesis molecularly imprinted polymer |
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