首页 | 本学科首页   官方微博 | 高级检索  
检索        

人类巨细胞病毒感染相关性传染性单核细胞增多症临床特点及治疗
引用本文:张胜,周涛,付四毛.人类巨细胞病毒感染相关性传染性单核细胞增多症临床特点及治疗[J].广州医学院学报,2007,35(2):52-54.
作者姓名:张胜  周涛  付四毛
作者单位:广东省中山市博爱医院儿科,广东,中山,528403
摘    要:目的:探讨人类巨细胞病毒(HCMV)相关性传染性单核细胞增多症的临床特点及治疗.方法:对9例确诊有CMV病毒感染且具备传染性单核细胞增多症临床特点的患儿进行回顾性资料分析及总结;并与21 例EB病毒相关传染性单核细胞增多症临床特点相比较.结果:与EB组(B组)比较,HCMV组(A组)感染患儿颈部淋巴结肿大少见(P<0.05),渗出性咽炎少(P<0.05),外周血异型淋巴细胞增高程度较低(P<0.05),皮疹多见(7/9例),嗜异性抗体常为阴性,HCMV组病例经更昔洛韦治疗1个月可以全部治愈.EB组(B组)颈部多发性淋巴结肿大较多见,渗出性咽炎发生率高,外周血异型淋巴细胞增高程度明显,嗜异性抗体常为阳性.结论:HCMV病毒可引起传染性单核细胞增多症,其临床特点与EB病毒相关传染性单核细胞增多症有所不同,更昔洛韦是一种有效的治疗药物.

关 键 词:巨细胞病毒  传染性单核细胞增多症  疾病特征
文章编号:1008-1836(2007)02-0052-03
修稿时间:2006-11-11

The Clinical Features and Treatment of the Infectious Mononucleosis Syndrome Related to Human Cytomegalovirus Infection
ZHANG Sheng,ZHOU Tao,FU Si-mao.The Clinical Features and Treatment of the Infectious Mononucleosis Syndrome Related to Human Cytomegalovirus Infection[J].Academic Journal of Guangzhou Medical College,2007,35(2):52-54.
Authors:ZHANG Sheng  ZHOU Tao  FU Si-mao
Institution:Dept of Pediatrics ,Boai Hospital of Zhongshan City, Zhongshan 528403, Gnangdong, China
Abstract:Objective:To investigate the clinical features and treatment of the infectious mononucleosis syndrome related to human cytomegalovirus(HCMV) infection.Methods: Clinical features of 9 cases of infectious mononucleosis syndrome related to HCMV infection(group A),were retrospectively analyzed and compared with the clinical features of 21 cases of infectious mononucleosis syndrome related to Epstein-barr virus infection(group B).Results: In group A,the incidences of cervical lymphadenopathy,exudative pharyngitis,peripheral blood atypical lymphocyte were significantly lower than those in group B(P<0.05).Skin rash was more common,and heterophilic antibody usually negative.The infectious mononucleosis syndrome related to HCMV infection could be cured with one month Ganciclovir treatment.The incidences of cervical lymphadenopathy and exudative pharyngitis in group B were significantly higher than those in group A(P<0.05).Peripheral blood atypical lymphocyte increased obviously and heretophilic antibodies were often positive in group B.Conclusion: The clinical features of infectious mononucleosis syndrome related to HCMV infection were different from that related to Epstein-barr virus.Ganciclovir is an effective drug for treatment of HCMV infection.
Keywords:Cytomegalovirus  Infectious mononucleosis  disease attributes
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号