| 骨髓淋巴造血组织肿瘤的形态学和免疫表型分析 |
| |
| 引用本文： | 黄晓赤,罗克枢,王西川,赵剑萍,吴蓉宜.骨髓淋巴造血组织肿瘤的形态学和免疫表型分析[J].实用医院临床杂志,2010,7(3):39-42. |
| |
| 作者姓名： | 黄晓赤 罗克枢 王西川 赵剑萍 吴蓉宜 |
| |
| 作者单位： | 1. 成都市第六人民医院病理科,四川,成都,610051
2. 成都军区总医院病理科,四川,成都,610083 |
| |
| 摘 要： | 目的探讨骨髓活检(BMB)中淋巴造血组织肿瘤的临床病理特征和免疫表型特点,提高诊断水平。方法 19例骨髓的淋巴造血组织肿瘤行苏木精-伊红染色法(HE)染色、过碘酸雪夫氏染色法(PAS)染色、网状纤维染色及免疫组化PV9000法系列抗体标记。结果 4例骨髓增生异常综合征(MDS)均显示造血组织增生,有小巨核细胞和原始细胞异常定位;2例急性髓系白血病(AML)有显著原始粒细胞或原始红细胞增生;2例慢性粒细胞白血病(CML)显示粒系细胞增生为主,各阶段粒细胞均可见到;3例浆细胞性骨髓瘤(PCM)和8例非霍奇金淋巴瘤(NHL)均系骨髓肿瘤性增生,两者的HE形态结合免疫组化标记能够诊断和鉴别诊断。结论 MDS诊断主要依赖病理形态学,免疫组化标记没有太大帮助;对AML、CML、PCM和NHL的诊断而言,除病理形态学观察外,各类肿瘤组织免疫组化表型分析有重要参考价值。
|
| 关 键 词： | 骨髓活检 造血系统肿瘤 淋巴组织肿瘤 形态学 免疫组织化学 |
Tumors of lymphatic and hematopoietic tissue in bone marrow biopsy:Analysis of morphology and immunophenotype |
| |
| HUANG Xiao-chi,LUO Ke-shu,WANG Xi-chuan,ZHAO Jian-ping,WU Rong-yi.Tumors of lymphatic and hematopoietic tissue in bone marrow biopsy:Analysis of morphology and immunophenotype[J].Practical Journal of Clinical Medicine,2010,7(3):39-42. |
| |
| Authors: | HUANG Xiao-chi LUO Ke-shu WANG Xi-chuan ZHAO Jian-ping WU Rong-yi |
| |
| Institution: | HUANG Xiao-chi1,LUO Ke-shu2,WANG Xi-chuan1,ZHAO Jian-ping1,WU Rong-yi1 (1.Department of Pathology,Chengdu Sixth People\'s Hospital,Chengdu 610051,China,2.Department of Pathology,General Hospital of Chengdu Military Comm,,Chengdu 610083,China) |
| |
| Abstract: | Objective To study the clinical and pathological features of lymphatic and hematopoietic tissue tumors in bone marrow biopsy for the improvement of diagnosis.Methods Nineteen cases of lymphatic and hematopoietic tissue tumors in bone marrow biopsy were studied by HE stain,PAS stain,reticulin stain and PV9000 antibody labeling.Results Hematopoietic tissue hyperplasia and abnormal localization of small megakaryocyte and immature precursors appeared in 4 cases of myelodysplastic syndromes (MDS).Myeloblast or p... |
| |
| Keywords: | Bone marrow biopsy hematopoietic tissue tumors Lymphatic tissue tumors Morphology Immunohistochemistry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
