| HPLC法测定贞芪扶正薄膜衣片中齐墩果酸的含量 |
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| 引用本文： | 梁琪,马君义,袁才英. HPLC法测定贞芪扶正薄膜衣片中齐墩果酸的含量[J]. 中国医药指南, 2012, 0(25): 437-438 |
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| 作者姓名： | 梁琪 马君义 袁才英 |
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| 作者单位： | 1. 西北师范大学生命科学院,甘肃 兰州 730070
2. 甘肃新兰药药业有限公司,甘肃 兰州 730070 |
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| 摘 要： | 目的建立贞芪扶正薄膜衣片的含量测定方法。方法采用高效液相色谱法测定贞芪扶正薄膜衣片中齐墩果酸的含量。流动相:乙腈-甲醇-水-乙酸铵(70∶16∶14∶0.5);流速为1.0mL/min,检测波长:215nm;柱温为室温。结果在0.00824～2.06mg/mL范围内线性关系良好(r=0.9999),线性方程为y=9905.62+2012.30x。平均回收率为99.57%,RSD=1.01%(n=5)。结论所建立的方法简便、快速,结果可靠、准确,可用于贞芪扶正薄膜衣片的质量控制。
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| 关 键 词： | 贞芪扶正薄膜衣片 齐墩果酸 女贞子 |
HPLC Determination Zhenqifuzheng Film-coated Tablets of Oleanolic Acid Content |
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| LIANG Qi,MA Jun-yi,YUAN Cai-ying. HPLC Determination Zhenqifuzheng Film-coated Tablets of Oleanolic Acid Content[J]. Guide of China Medicine, 2012, 0(25): 437-438 |
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| Authors: | LIANG Qi MA Jun-yi YUAN Cai-ying |
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| Affiliation: | 1 College of life Science of Northwest Normal University,Lanzhou 730070,China;2 Gansu xinlanyao pharmaceutical Group Co.Ltd.,Lanzhou 730070,China) |
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| Abstract: | Objective To determine the contents of the Zhenqifuzheng film-coatd tables by HPLC.Methods The HPLC method was established for the content determination of oleanolic acid in the Zhenqifuzheng film-coatd tables,was used with a mobile phase consisting of acetonitrile-methanol-waterammonium acetate（70：16：14：0.5）,the flow rare was 1.0 mL/min,the detection wavelength was 215 nm,and the column tempreture was room temperature.Results A good linearity was obtained in the range of 0.00824~2.06mg/mL（r= 0.9999）,linear equation is y=9905.62＋2012.30x,the average recovery was 99.57% with RSD of 1.01%（n=5）.Conclution The established method is simple,fast,reliable,accurate,and can be used as quality control of the Zhenqifuzheng film-coatd tables. |
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| Keywords: | Zhenqifuzheng film-coatd tables Oleanolic acid Ligustrum LucidumAit |
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