Fundamental aspects of the developing brain: synapse formation |
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Authors: | S Pelc |
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Affiliation: | Department of Child Neurology, the University of Brussels and Saint-Pierre University Hospital, Brussels |
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Abstract: | The phenomena presiding over synaptogenesis in the developing brain, notably death of neurons and the nerve growth factor are described as well as the neurobiological and ultrastructural features of synapse maturation. Synapse and connection specificity in the brain versus plasticity are given consideration. Infantile neuroaxonal dystrophy is suggested as a possible example of defective synaptogenesis. |
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Keywords: | Synapse formation connection specificity plasticity developing brain infantile neuroaxonal dystrophy |
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