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Fundamental aspects of the developing brain: synapse formation
Authors:S Pelc
Affiliation:Department of Child Neurology, the University of Brussels and Saint-Pierre University Hospital, Brussels
Abstract:The phenomena presiding over synaptogenesis in the developing brain, notably death of neurons and the nerve growth factor are described as well as the neurobiological and ultrastructural features of synapse maturation. Synapse and connection specificity in the brain versus plasticity are given consideration. Infantile neuroaxonal dystrophy is suggested as a possible example of defective synaptogenesis.
Keywords:Synapse formation  connection specificity  plasticity  developing brain  infantile neuroaxonal dystrophy
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