Recidiva cerebral en paciente con linfoma cardíaco primario

We report the case of a patient diagnosed of primary cardiac lymphoma who was treated by partial surgery and six cycles of CHOP chemotherapy. After 6 months free of tumor, she showed isolated intracerebral relapse for wich received holocraneal radio-therapy: complete response. Nine months later, the tumor was found in the brain again and it was treated by radiosurgery, but ultimate she died from progressive cerebral disease. The review of the literature, advise us about the possibility of intracerebral relapse in primary cardiac lymphomas as a characteristic event, and in consequence, perhaps we need drugs that cross better the blood-brain barrier.