难治性心力衰竭继发肺部真菌感染的病原学分析及防治研究

目的探讨难治性心力衰竭继发肺部真菌感染的病原学情况,且加强预防控制措施,以降低该疾病的发生,控制病情进展。方法回顾性分析2011年1月至2014年1月40例难治性心力衰竭继发肺部真菌感染患者,采用纸片扩散法进行细菌培养和药敏试验,进行病原学分析,并总结防治措施。结果 40例患者中培养出病原菌50株,其中以白色念珠菌为主占40%;耐药性上,所有真菌均对两性霉素B无耐药性,均为0,余以伏立康唑、卡泊芬净为主,其他的耐药性普遍较高。临床效果上,治愈率为30%,总有效率92.5%。结论难治性心力衰竭继发肺部真菌感染耐药性较严重,在临床上加强防治措施后可取得一定的临床效果。

Etiology of Refractory Heart Failure Secondary to Pulmonary Fungal Infection and Prevention and Treatment Measures Research

Objective To investigate the refractory heart failure secondary to pulmonary fungal infection in the etiology of the situation, and to strengthen the prevention and control measures to reduce the incidence of the disease control disease progression. Methods A retrospective analysis from January 2011 to December 2014, 40 cases of refractory heart failure in patients with secondary pulmonary fungal infections, bacterial culture and sensitivity testing using the disk diffusion method, etiology analyze and summarize preventive measures. ResuRs 40 patients cultured pathogen 50, of which candida albicans, accounting for 40%; drug resistance, all the fungi to amphotericin B were no drug resistance, are 0, I to V force itraconazole, caspofungin-based, and other resistance generally higher. Clinical effect, the cure rate was 30%, the total efficiency of 92.5%. Conclusion Refractory heart failure secondary to pulmonary fungal infection resistance more serious, after strengthening preventive measures can be obtained in clinical some clinical results.