| 氨曲南治疗肿瘤患者下呼吸道感染的临床疗效观察 |
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| 引用本文： | 周燕萍.氨曲南治疗肿瘤患者下呼吸道感染的临床疗效观察[J].中国药房,2006,17(3):202-203. |
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| 作者姓名： | 周燕萍 |
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| 作者单位： | 武警重庆总队医院药剂科,重庆市,400061 |
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| 摘 要： | 目的观察氨曲南治疗肿瘤患者下呼吸道感染的临床疗效和安全性。方法将170例恶性肿瘤伴下呼吸道感染患者随机分为氨曲南2.0g治疗组85例(A组)和头孢他啶2.0g对照组85例(B组),q12h,疗程均为7d~14d。比较2组临床疗效、细菌学改变及不良反应情况。结果A、B组临床有效率分别为87.06%、83.35%,细菌清除率分别为92.54%、86.76%,二者比较无显著性差异(P>0.05)。结论氨曲南治疗肿瘤患者下呼吸道感染安全、有效。
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| 关 键 词： | 氨曲南 肿瘤患者 下呼吸道感染 |
| 文章编号： | 1001-0408(2006)03-0202-02 |
| 收稿时间： | 12 12 2005 12:00AM |
| 修稿时间： | 01 12 2006 12:00AM |
Clinical Observation of Aztreonam in the Treatment of Cancer Patients with Lower Respiratory Tract Infection |
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| ZHOU Yanping.Clinical Observation of Aztreonam in the Treatment of Cancer Patients with Lower Respiratory Tract Infection[J].China Pharmacy,2006,17(3):202-203. |
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| Authors: | ZHOU Yanping |
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| Institution: | Chongqing General Hospital of Armed Polices,Chongqing 400061, China |
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| Abstract: | OBJECTIVE:To evaluate the efficacy and safety of aztreonam in the treatment of cancer patients with lower respiratory tract infection.METHODS:A total of170cases were randomly divided into study group and control group(each group have85patients),study group(group A)were treated by aztreonam2.0g,control group(group B)were treated by ceftazidime2.0g,q12h,all patients treated7～14days as a course.The clinical efficacy,the bacterial clearance rates and adverse drug reaction of2group were compared.RESULTS:The clinical efficacy rate of group A and B were87.06%and83.35%respectively,the bacterial clearance rates were92.54%and86.76%respectively,there were no statistical differences between2groups(P>0.05).CONCLUSIONS:Aztreonam is an effective and safe agent for treatment of cancer patients with lower respiratory tract infection. |
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| Keywords: | Atreonarn Cancer patients Lower respiratory tract |
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