| 冠心病患者氧化低密度脂蛋白自身抗体的变化 |
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| 引用本文： | 沈建昕,张三明,鲁翔. 冠心病患者氧化低密度脂蛋白自身抗体的变化[J]. 江苏医药, 2008, 34(11): 1106-1107 |
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| 作者姓名： | 沈建昕 张三明 鲁翔 |
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| 作者单位： | 河北北方学院第一附属医院检验科,张家口,075000;南京医科大学第二附属医院心脏病科 |
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| 摘 要： | 目的 探讨血清氧化低密度脂蛋白自身抗体(Ab-ox-LDL)与冠心病患者病变稳定性及病变程度的关系.方法 根据临床诊断标准和冠状动脉造影结果 ,将60例患者分为非冠心病(CON)组、不稳定型心绞痛(UAP)组和稳定型心绞痛(SAP)组,采用ELISA法测定血清Ab-ox-LDL浓度.结果 UAP组血清Ab-ox-LDL水平明显高于SAP和CON组(P＜0.05),SAP组高于CON组(P＜0.05);Ab-ox-LDL在UAP组和SAP组呈高度正相关(P＜0.05).结论 血清Ab-ox-LDL与冠心病患者病变的严重程度和冠心病斑块的稳定性密切相关,在冠状动脉硬化进程中可能起着重要的作用.
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| 关 键 词： | 氧化低密度脂蛋白 自身抗体 冠心病 |
The changes of autoantibody against oxidized low density lipoprotein in patients with coronary heart disease |
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| SHEN Jianxin,ZHANG Sanming,LU Xiang. The changes of autoantibody against oxidized low density lipoprotein in patients with coronary heart disease[J]. Jiangsu Medical Journal, 2008, 34(11): 1106-1107 |
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| Authors: | SHEN Jianxin ZHANG Sanming LU Xiang |
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| Affiliation: | SHEN Jianxin,ZHANG Sanming,LU Xiang. Clinical Laboratory,Affiliated First Hospital,Hebei North University,Zhangjiakou 075000,CHINA |
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| Abstract: | Objective To study the relationship of serum oxidezed low density lipoprotein autoantibody(Ab-ox-LDL)with the plaque stability and lesion degree of patients with coronary heart disease(CHD).Methods According to clinical diagnostic criteria of CHD and coronary angiography,sixty patients were allocated into non-coronary heart disease(group C),unstable angina pectoris(group UAP)and stable angina pectoris(group SAP).Serum levels of Ab-ox-LDL were measured with enzyme-linked immunosorbent assay method.Results Se... |
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| Keywords: | Autoantibody against oxidized low density lipoprotein Coronary heart disease |
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