Necrotizing granulomatous vasculitis associated with cocaine use |
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Authors: | Gertner Elie Hamlar Dave |
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Affiliation: | Department of Otolaryngology/Head and Neck Surgery, University of Minnesota Medical School, St. Paul, USA |
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Abstract: | Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction. This report is the first to document a necrotizing granulomatous vasculitis associated with nasal destruction and an oronasal fistula in a chronic cocaine user. Cocaine is an environmental insult that may play a role in triggering cerebral and non-cerebral vasculitis including a necrotizing granulomatous vasculitis of the respiratory tract. |
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