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| 维持性血液透析患者皮肤瘙痒与炎症的关系 | |
| 引用本文： | 苗艳,王建生,邵凤民.维持性血液透析患者皮肤瘙痒与炎症的关系[J].实用诊断与治疗杂志,2008,22(4):277-279. |
| 作者姓名： | 苗艳 王建生 邵凤民 |
| 作者单位： | 1. 河南省人民医院 2. 郑州大学第二附属医院肾内科,郑州市,450014 3. 河南省人民医院肾内科 |
| 摘 要： | 目的:观察慢性微炎症状态与维持性血液透析患者皮肤瘙痒的关系。方法:选择维持性血液透析伴皮肤瘙痒患者18例,维持性血液透析无皮肤瘙痒患者15例,健康对照者20例,所有研究对象均在清晨空腹抽取不抗凝静脉血(维持性血液透析33例患者在血透前、后采静脉血),分离血清后采用免疫比浊法检测C反应蛋白。结果:维持性血液透析患者C反应蛋白均明显高于对照组(P<0.05);维持性血液透析患者单次透析后C反应蛋白均高于透析前(P<0.05);维持性血液透析患者中伴皮肤瘙痒者C反应蛋白高于不伴皮肤瘙痒者(P<0.05)。结论:维持性血液透析患者存在微炎症状态,单次血液透析可能加重微炎症状态,引起皮肤瘙痒的原因可能与炎症相关。 |
| 关 键 词： | 维持性血液透析 皮肤瘙痒 慢性炎症状态 |
| 文章编号： | 1672-3457(2008)04-277-02 |
| 修稿时间： | 2008年3月10日 |
Association of pruritus and inflammation in maintenance hemodialysis patients |
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| MIAO Yan,WANG Jiansheng,SHAO Fengmin.Association of pruritus and inflammation in maintenance hemodialysis patients[J].Journal of Practical Diagnosis and Therapy,2008,22(4):277-279. | |
| Authors: | MIAO Yan WANG Jiansheng SHAO Fengmin |
| Abstract: | Objective To observe the relationship between pruritus and chronic microinflammatory state in maintenance hemodialysis patients.Methods The levels of C-reactive protein in 18 maintenance hemodialysis patients with pruritus and 15 maintenance hemodialysis patients without pruritus were measured and compared with 20 control subjects.Results The levels of C-reactive protein increased significantly(P<0.05) in maintenance hemodialysis patients with pruritus compared with maintenance hemodialysis patients without pruritus and control subjects.Conclusion Inflammation may play a role in pruritus in maintenance hemodialysis patients. |
| Keywords: | Maintenance hemodialysis pruritus chronic microinflammatory state |
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