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直线加速度所致的猫弥漫性轴突损伤
引用本文:王汉东,段国升.直线加速度所致的猫弥漫性轴突损伤[J].中华神经外科杂志,1997,13(1):31-33.
作者姓名:王汉东  段国升
作者单位:南京军区南京总医院神经外科,解放军总医院神经外科
摘    要:目的:为了解直线加速度在颅脑损伤特别是在弥漫性轴突损伤(DAI)中的作用。方法:用一套撞击装置对26只猫进行实验。结果:直线加速度可以导致几乎所有类型的颅脑损伤,包括颅骨骨折、蛛网膜下腔出血、硬膜下血肿、硬膜外血肿、脑挫伤、脑干损伤,特别是DAI。DAI的特征性改变-轴突回缩球在24小时内死亡的动物脑标本中看不到,24小时后可见到,72小时则多而典型,7天时仍然存在。结论:凡能使脑的神经纤维受到广泛剪力和(或)张力的任何形式的外部作用均可产生DAI。

关 键 词:颅脑损伤  直线加速度  弥漫性轴突损伤  轴突

Diffuse axonal injury of the cat induced by linear acceleration force
Wang Hangdong,Duan Guo sheng,Zhang Ji,et al..Diffuse axonal injury of the cat induced by linear acceleration force[J].Chinese Journal of Neurosurgery,1997,13(1):31-33.
Authors:Wang Hangdong  Duan Guo sheng  Zhang Ji  
Institution:Wang Hangdong,Duan Guo sheng,Zhang Ji,et al. Dept. of Neurosurgery Postgraduate Medical School of PLA,Beijing 100853
Abstract:Objective: To observe on linear acceleration force on the traumatic changes of the brain, especially on the evolution of the diffuse axonal injury (DAI) in cats. Methods: An impact device to deliver a linear acceleration force was used to set up head injured models in 26 cats. Results: The axonal retraction balls (ARB) were invisible within 24 hours after trauma, but often occurred 24 hours later. The ARB showed classic and a large amount after 72 hours, and still remained somewhat in 7 day. Conclusion: Any external force which could cause shear or tensile strain to the axons of the brain would DAI induce.
Keywords:Head injury  Linear acceleration force  Diffuse axonal injury(DAI)  Brain retraction ball  
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