| 正交试验优选雷公藤涂膜剂的基质组成 |
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| 引用本文： | 钱丽萍,阙慧卿,林 绥,彭华毅,郭舜民. 正交试验优选雷公藤涂膜剂的基质组成[J]. 医学教育探索, 2011, 34(6): 442-444 |
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| 作者姓名： | 钱丽萍 阙慧卿 林 绥 彭华毅 郭舜民 |
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| 作者单位： | 福建省医学科学研究院，福建 福州 350001 |
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| 基金项目： | 福建省科技重大专项（2009YZ0001-1-3）；福建省医学创新项目（2009-CX-16）；福建省省属公益类科研院所基本科研专项（2011R1034-3） |
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| 摘 要： | 目的 优选雷公藤涂膜剂基质的组成和配比。方法 采用正交试验法，以外观质量、成膜时间为指标，确定基质中不同辅料的最佳配比。结果 以聚乙烯醇-124、CMC-Na、甘油比例为4∶1∶2制得的涂膜剂最稳定。结论 优选得到的配方设计合理，制备工艺简单，质量可控，可以为工业生产提供理论基础。
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| 关 键 词： | 雷公藤涂膜剂；正交设计；基质组成；涂膜剂 |
Optimization on metrical composition in Tripterygium Plastics by orthogonal test |
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| QIAN Li-ping,QUE Hui-qing,LIN Sui,PENG Hua-yi,GUO Shun-min. Optimization on metrical composition in Tripterygium Plastics by orthogonal test[J]. Researches in Medical Education, 2011, 34(6): 442-444 |
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| Authors: | QIAN Li-ping QUE Hui-qing LIN Sui PENG Hua-yi GUO Shun-min |
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| Affiliation: | Fujian Academy of Medical Sciences, Fuzhou 350001, China |
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| Abstract: | Objective To optimize the metrical composition and its ratio in Tripterygium Plastics. Methods The best ratio of different materials in the matrix was determined by orthogonal test, using appearance quality and film-forming time as index. Results The best ratio of PVA-124, CMC-Na, and glycerol for making the most stable plaster was 4:1:2. Conclusion The optimized formulation is well designed with simple preparation process and controllable quality, which could provide a theoretical basis for industrial production. |
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| Keywords: | Tripterygium Plaster orthogonal design metrical composition Plastics |
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