透明细胞型肝癌的临床病理特点及预后分析15例

目的:探讨透明细胞型肝癌(primary clear cell carcinoma of the liver,PCCCL)的临床病理特点及预后影响因素.方法:对1997-01/2007-03手术治疗的15例PCCCL患者的临床、病理特点及预后因素进行回顾性分析.结果:PCCCL患者的1-,3-,5年的总生存率分别为97%、60%和60%.肿瘤大小是PCCCL患者无瘤生存率的独立预后因素,肿瘤分化是PCCCL患者总生存率的独立预后因素.结论:PCCCL为肝细胞肝癌的一种少见的病理类型.手术切除是PCCCL最佳治疗手段,与文献报道相比,预后好于其他病理类型的HCC.

Clinicopathologic characteristics and prognostic factors of primary clear cell carcinoma of the liver:An analysis of 15 cases

AIM:To investigate the clinicopathologic characteristics and prognostic factors of primary clear cell carcinoma of the liver(PCCCL).METHODS:The clinical data for 15 PCCCL patients treated by curative resection from January 1997 to March 2007 were retrospectively analyzed.RESULTS:The 1-,3-,and 5-year overall survival(OS) rates of PCCCL patients were 97%,60% and 60%,respectively.Tumor size was an independent risk factor for disease-free survival(DFS) of PCCCL,while tumor differentiation was an independent risk factor for OS of PCCCL.CONCLUSION:PCCCL is an uncommon subtype of HCC,and complete surgical resection is the optimal treatment for PCCCL.The prognosis of PCCCL is better than that of other types of HCC.