宫颈冷刀锥切术诊治宫颈上皮内瘤变的价值

目的]探讨宫颈冷刀锥切术对宫颈上皮内瘤变(CIN)的诊断及治疗作用.方法]对比126例行宫颈冷刀锥切术和阴道镜下多点活检的CIN患者的病理检查结果,分析CIN患者行宫颈冷刀锥切术的临床疗效和并发症.结果]阴道镜下多点活检和宫颈冷刀锥切术后病理完全符合83例(占65.9％).14例(11.1％)患者锥切边缘受累；发现早期浸润癌5例,其中2例早期浸润癌仅行宫颈锥切,随访无复发.宫颈冷刀锥切术的主要并发症为出血和宫颈管狭窄,发生率分别为6.3％ (8/126)和3.9％ (5/126).结论]宫颈锥切术比阴道镜下多点活检对宫颈上皮内瘤变的诊断更准确,并具有重要治疗作用.

Value of Cervical Cold Knife Conization in the Diagnosis and Treatment for Cervical Intraepithelial Neoplasia

Purpose] To investigate the diagnostic and therapeutic efficacy of cold knife conization for cervical intraepithelial neoplasia(CIN).Methods] Pathologic findings of cervical cold knife conization and colposcopic multiple punch biopsies were compared in 126 cases with CIN,and the clinical efficacy and complications of cold knife conization were analyzed.Results] Pathologic findings of colposcopic multiple punch biopsies and cervical cold knife conization were full compliance in 83 cases(65.9%).Conization margin involved in 14 cases,and early invasive cancer in 5 cases were found.Two cases with early invasive cancer were treated with conization alone without recurrence in the follw-up period.The main complications associated with conization were haemorrhage(6.3%,8/126) and cervical stenosis(3.9%,5/126).Conclusion] CIN diagnosis with conization is more accurate than that with colposcopic multiple punch biopsies.And it plays an important role in the treatment for CIN and early invasive cancer.