| 红树植物卤蕨化学成分的分离与鉴定 |
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| 引用本文： | 梅文莉,曾艳波,丁中涛,戴好富.红树植物卤蕨化学成分的分离与鉴定[J].中国药物化学杂志,2006,16(1):46-48,64. |
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| 作者姓名： | 梅文莉 曾艳波 丁中涛 戴好富 |
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| 作者单位： | 1. 中国热带农业科学院,热带生物技术研究所,热带作物生物技术国家重点实验室,海南,海口,571101
2. 云南大学,化学系,云南,昆明,650091 |
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| 基金项目： | 中国热带农业科学院科技基金;海南省自然科学基金 |
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| 摘 要： | 目的 对红树植物卤蕨（Acrostichum aureurm）的化学成分进行研究。方法 用多种色谱技术对化合物进行分离纯化。并根据化合物的理化性质及波谱数据鉴定化合物的结构。经MTT法进行体外抗肿瘤活性测试。结果 从卤蕨乙醇提取物中分离得到6个化合物，分别鉴定为ponasteroneA（1）、pterosterone（2）、山奈酚（3）、槲皮素（4）、4-（3。4-二羟基苯基）-2-丁酮（5）、胡萝卜苷（6）。结论 6个化合物均为首次从该植物中分离得到。初步的药理试验表明6个化合物对小鼠B16细胞均无生长抑制活性。
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| 关 键 词： | 药物化学 结构鉴定 柱色谱法 卤蕨 化学成分 |
| 文章编号： | 1005-0108(2006)01-0046-03 |
| 收稿时间： | 2005-07-25 |
| 修稿时间： | 2005-07-25 |
Isolation and identification of the chemical constituents from Mangrove plant Acrostichum aureurm |
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| MEI Wen-li,ZENG Yan-bo,DING Zhong-tao,DAI Hao-fu.Isolation and identification of the chemical constituents from Mangrove plant Acrostichum aureurm[J].Chinese Journal of Medicinal Chemistry,2006,16(1):46-48,64. |
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| Authors: | MEI Wen-li ZENG Yan-bo DING Zhong-tao DAI Hao-fu |
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| Institution: | 1. State Key Laboratory of Tropical Crops Biotechnology, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agriculture Sciences, Haikou 571101, China ; 2. Department of Chemistry, Yunnan University, Kunming 650091, China |
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| Abstract: | Aim To study the chemical constituents of Acrostichum aureurm.Methods The constituents were isolated and purified by column chromatography,and their structures were identified by physicochemical data and spectral data.Results Six compounds were isolated from the ethanol extracts of Acrostichum aureurm,and their structures were elucidated as ponasterone A(1),pterosterone(2),kaempferol(3),quercetin(4),4-(3,4-dihydroxyphenyl)-2-butanone(5),and daucosterol(6),respectively.Conclusion All the compounds are isolated from this plant for the first time,and show no growth inhibitory activity on murine melanoma B_(16) cells by MTT assay. |
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| Keywords: | medicinal chemistry structural identification column chromatography Acrostichum aureurm chemical constituents |
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