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小剂量阿斯匹林对冠心病患者血浆脂质过氧化物的影响
引用本文:余钟声,钟雪娟. 小剂量阿斯匹林对冠心病患者血浆脂质过氧化物的影响[J]. 中华急诊医学杂志, 1994, 0(3)
作者姓名:余钟声  钟雪娟
作者单位:浙江医科大学附属儿童医院儿科研究所!杭州310003(余钟声),杭州市第三医院内科!杭州310009(钟雪娟)
摘    要:检测了45例冠状动脉粥样硬化性心脏病患者的血浆脂质过氧化物的含量,发现患者含量比正常对照组要明显增高(P<0.0001)。单用阿斯匹林40mg/d治疗患者,4个月后,测号血浆脂质过氧化物含量明显下降(P<0.001)。结果提示,血浆脂质过氧化物含量的增高可能是动脉粥样硬化的一个重要因素,小剂量阿斯匹林可明显抑制脂质过氧化。

关 键 词:冠心病  脂质过氧化物  阿斯匹林

The Effects of Low-dose Aspirin on Lipoperoxide Content of Coronary Atherosclerotic Heart Disease
Yu Zhongsheng,Zhong Xuejuan. The Effects of Low-dose Aspirin on Lipoperoxide Content of Coronary Atherosclerotic Heart Disease[J]. Chinese Journal of Emergency Medicine, 1994, 0(3)
Authors:Yu Zhongsheng  Zhong Xuejuan
Abstract:Plasma lipid peroxides (LPO) contents were studied in 45 patients with atherosclerotic heart disease (AHD) and 31 normal individuals. LPO contents of patients were significantly higher as compared with the healthy subjects (P<0. 001). After patients were treated using low dosage of aspirin for four morths,LPO contents were significantly decreased (P <0.001). It is indicated that the imbalance of LPO may be an important facter responsible for atherosclerosis and low-dose aspirin may inhibit LPO in AHD.
Keywords:atherosclerotic heart disease aspirin lipoperoxide
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